Intestinal microbiota of culicidae and its relation with the insecticide resistance: a review

Abstract

Members of the Culicidae family have great sanitary importance for being vectors of diseases such as dengue, yellow fever, zika virus among others. For combat, the use of insecticides is still the most used form globally, although there are already reports of resistance of these mosquito populations to this means of control. There are several studies relating the mechanisms of defense of insects, since the adaptation of their enzymatic activity, which degrades xenobiotics, as changes in behavior. In addition, some recent studies have related the participation of intestinal microbiota in the process of resistance to insecticides. Therefore, the present review sought to collect studies on the identification of bacteria present in the intestinal tract of culicides, the means of resistance to insecticides, as well as the correlation of their microbiota with this process. To do so, it sought publications in the PubMed, Scielo and Research Gate databases, and added the main findings on the suggested theme. It became evident that these insects have several defense mechanisms against the various insecticides used, focusing on their enzymatic activity, and some studies also reported the aid of intestinal microbiota in the resistance process. In view of these results, it becomes evident the need to search for new forms of combat, since the dispersion of such diseases causes great misfortune to several regions of the globe.